經(jīng)過(guò)評(píng)估，專家小組認(rèn)為該添加劑對(duì)目標(biāo)物種、消費(fèi)者和環(huán)境是安全的。由于缺乏數(shù)據(jù)，研究小組無(wú)法就該添加劑對(duì)皮膚或眼睛產(chǎn)生刺激的可能性得出結(jié)論。評(píng)估中的添加劑被認(rèn)為是非反芻動(dòng)物物種氨基酸L-精氨酸的有效來(lái)源。為了使補(bǔ)充的L-精氨酸對(duì)反芻動(dòng)物和非反芻動(dòng)物同樣有效，需要防止其在瘤胃中降解。部分原文報(bào)道如下：

　　

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the feed additive consisting of l-arginine produced by fermentation with a genetically modified strain of Escherichia coli (CGMCC 7.401). The additive is intended to be used in feed and water for drinking for all animal species and categories. The genetic modifications introduced do not raise safety concerns. No viable cells or DNA of the production strain were detected in the final product. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive does not pose any safety concern with regard to the production strain. l-Arginine produced with E. coli CGMCC 7.401 is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species. The FEEDAP Panel has concerns on the use of amino acids in water for drinking for hygienic reasons, and due to the risk of imbalances when administered simultaneously via feed and water. The use of l-arginine produced with E. coli CGMCC 7.401 in animal nutrition is considered safe for the consumers and for the environment. The endotoxin activity of the additive does not represent a hazard for persons handling the additive. In the absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and/or eyes, or to be a dermal or respiratory sensitiser. The additive l-arginine produced with E. coli CGMCC 7.401 is regarded as an efficacious source of the essential amino acid l-arginine for non-ruminant species. For supplemental l-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen.

　　

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