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當(dāng)前位置: 首頁 » 食品資訊 » 外訊導(dǎo)讀 » 歐盟評估轉(zhuǎn)基因米曲霉菌株 NZYM-FL生產(chǎn)的三酰甘油脂肪酶的安全性

歐盟評估轉(zhuǎn)基因米曲霉菌株 NZYM-FL生產(chǎn)的三酰甘油脂肪酶的安全性

放大字體  縮小字體 時(shí)間:2024-12-20 10:25 來源:食品伙伴網(wǎng) 作者: 澤夕   
核心提示:2024年12月18日,歐盟食品安全局就一種食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性評價(jià)發(fā)布意見。
   食品伙伴網(wǎng)訊  2024年12月18日,歐盟食品安全局就一種食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性評價(jià)發(fā)布意見。
  
  據(jù)了解,這種食品酶是由轉(zhuǎn)基因米曲霉菌株 NZYM-FL生產(chǎn)的,旨在用于兩種食品生產(chǎn)過程。
  
  經(jīng)過評估,專家小組得出結(jié)論,該食品酶在預(yù)期的使用條件下不會引起安全問題。部分原文報(bào)道如下:
  
  The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the genetically modified Aspergillus oryzae strain NZYM-FL by Novozymes A/S. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that, under the intended conditions of use, this food enzyme did not give rise to safety concerns. Due to the implementation of a new methodology to estimate the dietary exposure to food enzymes in 2016, the European Commission requested EFSA to revise the exposure assessment of this food enzyme by using this new methodology. In this assessment, EFSA realigned the intended uses of this food enzyme to two food manufacturing processes and recalculated the dietary exposure. As the food enzyme-total organic solids (TOS) are removed in one food manufacturing process, the dietary exposure to the food enzyme-TOS was estimated only for the remaining process. It was calculated to be up to 0.492 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (340 mg TOS/kg bw per day, the mid-dose tested), the Panel derived a margin of exposure of at least 691. based on the revised exposure estimate, the margin of exposure calculated thereof and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
  
  本文由食品伙伴網(wǎng)食品資訊中心編輯,供網(wǎng)友參考,有任何疑問,請聯(lián)系news@foodmate.net。
日期:2024-12-20
 
 
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